CAS No. Registry Number: 8028-98-6

Herb Name    Murraya paniculata(L.) Jack (=M. exotica L.)
Scientific Name    Rutaceae
Local Name    Jin-li-xiang(C),Gou-lee-heung(H),Gekkitsu(J)
Part     Leaf
Local Drug Name    Jin-li-xiang(C),Gou-lee-heung(H)
Processing    Fresh or dry in shade
Adminstration    Oral or topical(decoction:C,H)
Medicinal Uses    Traumatic injury(C,H)
 Rheumatalgia(C,H)
 Ulcer pain,toothache(C,H)
 Stomach ache(C)
 Epidemic encepahlitis B(C,H)
 Absecess(C)
 Pruritus(C)
 Eczema(C)
 
Part     Root
Local Drug Name    Jiu-li-xiang-gen(C),Gou-lee-heung-gun(H)
Processing    Dry under the sun
Adminstration    Oral or topical(decoction:C,H)
Medicinal Uses    Rheumatalgia(C,H)
 Lumbago(C)
 Traumatic injury(C)
 Tinea(C)
 Eczema(C)
 Bronchitis(C)
 
 Chemistry
1) Leaf contains volatile oil composed predominantly of sesquiterpenoids :
2) Alkaloids : Noracronycine,de-N,N-methylnoracronycine,de-N-methylacronycine,skimmianine,mahanimbine,murrayazoline,yuehchukene(root),paniculol(leaf)
3) Aurantiamide acetate(stem bark) :
4) Coumarins : Phebalosin,paniculatin,murrayone,aurapten,murralongin,murrahgatin,meragin hydrate,imperatorin,murralonginol isovalerate,isomurralonginol isomurralonginol isovalerate,murrangatin isovalerate,minumicrolin isovalerate,chloculol,paniculonol isovalerate,isomurrlonginol nicotinate,panial,cis-osthenon,paniculin,murpaniculol,paniculal,coumurrin(leaf ofM.paniculata);murrayanone,murraculatin(leaf of M.paniculata var. omphalo-carpa);peroxyauraptenol,cis-dehydroosthol,murraol,murranganon,isomurranganon senecioate,murrangatin acetate,isomurralonginol acetate,chlotical,peroxymurraol,murraxocin,aurapten,osthol,(+)-erythromurangatin,(-)-minumicrolin,murralongin(leaf of M. exotica);paniculidines A,B and C,murralongin,osthol,3-(1,1-dimethylally)xanthyletin(root bark)
5) Murrayacarine,3-formylindole,imphalocarpin,5,5-dimethoxy-8-(3'-methyl-2'-oxobutyl)coumarin,coumurrayin,murragleinin,omphamurin,murraol,murracarpin,mupanidin,mexoticin,murrangatin,ferulyl esters(root bark of M. paniculata var.omphalocarpa) :
6) From flower of M. paniculata var. omphalocarpa : omphalocarpin,(-)-murracarpin,murrayacarpin-A and -B,scopolin,scopoletin,5,7-dimethyoxy-8-(3'-methyl-2'oxobutyl)coumarin,(+,-)-murracarpin,mupanidin
7) Sitosterol-β-d-galactoside : colensenone, colensanone
8) Glycoprotein,polysaccharide :
 9) Flavonoids : 3,5,6,7,8,3',4',5'-octamethoxyflavone,3,5,6,7,3',4',5'-heptamethoxyflavone,5,6,7,3',4',5'-hexamethoxyflavone,5,6,7,3',4'-pentamethoxyflavone,3,5,7,3',4',5'-hexamethoxyflavone,3,5,7,8,3',4',5'-heptamethoxyflavone
10) Protein polysaccharide
11) Cycloartenols : lupeol,3-epi-cycloaudenol

Pharmacology

 1) Anti-implantation effects  
 2) Antithyroid effects  
 3) LD50 of methanol-water extract of bark and leaf are both >1 g/kg I.p. in mice 
 4) Abortifacient effects   
 5) Antiinflammatory effects    
 6) Anticoagulant effects  
 7) Antiferility effects  
 8) LD50 of protein polysaccharide = 462 mg/kg I.p. in mice
 9) Antimicrobial effects