SFE Extract

Supercritical Fluid Extraction, SFE CO2-SFE

Supercritical extraction is not widely used yet, but as new technologies are coming there are more and more viewpoints that could justify it, as high purity, residual solvent content, environment protection.

Advantages

• Dissolving power of the SCF is controlled by pressure and/or temperature
• SCF is easily recoverable from the extract due to its volatility
• Non-toxic solvents leave no harmful residue
• High boiling components are extracted at relatively low temperatures
• Separations not possible by more traditional processes can sometimes be effected
• Thermally labile compounds can be extracted with minimal damage as low temperatures can be employed by the extraction

Disadvantages

• Elevated pressure required
  • Compression of solvent requires elaborate recycling measures to reduce energy costs
  • High capital investment for equipment

Changsha Organic Herb Inc. offer bellow listed products which are produced by SFE extraction:

1. Magnolia bark Extract powder Honokiol 90% Magnolol 90%
2. Decaffeinated Green Tea Leaf
3. Decaffeinated Coffee
4. Hop flowers Extract Polyphenols
5. Cnidium Fruit Extract Osthole
6. Salvia miltiorrhiza Extract Tanshinone ⅡA

Supercritical fluid extraction of magnolia bark with carbon dioxide (CO2) was performed at pressure 5800 psi, temperature 80°C, dynamic extraction time of 40 min and liquid CO2 flow rate of 2 mL/min. Preliminary screening of the extracts against S. aureus and M. smegmatis was performed using the Kirby-Bauer disc diffusion method. A microdilution method using a 96-well microtitre plate was developed for rapid and economical determination of the MIC of the extracts. The interaction of extracts with standard antibiotics, streptomycin and rifampicin, was determined from the FIC values obtained using the chequerboard method. Interactions were categorized by the FIC values as synergistic (FIC ≤ 0.05), indifferent (0.05 < FIC ≤4.0) or antagonistic (FIC > 4).